The Arizona Cardinals have allowed 40-plus points in consecutive games for the first time since 2002. These five plays explain why that's happened.

The Arizona Cardinals were not the NFL's most talented team during the second year of coach Jonathan Gannon's tenure, but they were among the most disciplined, committing the league's second-fewest penalties in 2024.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

Wilson caught 15 passes for 185 yards, coming close to matching in one game his entire season's production previously.

The two AFC West squads will face off in the desert on Sunday afternoon. After six weeks of dealing with turf toe, San Francisco 49ers quarterback Brock Purdy will be back in action on Sunday, Nov. 16 as his team travels to take on the Arizona Cardinals.

Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against the Arizona Cardinals during the fourth quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images / Darren Yamashita-Imagn Images

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host Cardinals (3-7).

With a 3-7 record, Arizona Cardinals head coach Jonathan Gannon is facing rumors about whether he will coach the team moving forward.

The Cardinals are suffering another injury at running back, causing further problems for a struggling Arizona squad.