The AFC South race has gotten significantly tighter in recent weeks. The Indianapolis Colts' lead in the division is now down to one game over the Jacksonville Jaguars and two games over the Houston Texans.

Houston Texas pick up third NFL victory in a row as Buffalo Bills quarterback Josh Allen sacked eight times in defeat; Allen threw for 253 yards without a touchdown after accounting for six touchdowns in a win over Tampa Bay last week;

Week 13 gets underway with a Thanksgiving Day tripleheader, leading off with the Green Bay Packers visiting the Detroit Lions (-2.5) in an NFC North clash. The Kansas City Chiefs (-3) and Dallas Cowboys meet up in the second game of the day, and the Cincinnati Bengals and Baltimore Ravens (-6.5) close out the action.

The Buffalo Bills signed veteran receiver Brandin Cooks before Sunday's crucial AFC showdown with Pittsburgh Steelers, seeking offensive spark after recent struggles.

Here's everything you need to know when the Houston Texans play the Indianapolis Colts Week 13 of the 2025 NFL season.