Oregon football got its 42-27 home victory against USC
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College Football Week 13 Takeaways
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If USC beats UCLA next week, it will have nine wins. That’s better than most rational observers would have expected.
As expected, there was no change around the top-dozen of the Coaches Poll top 25 college football rankings, but losses by lower-placed teams allowed some moveme
Week 13 was relatively quiet, as a handful of SEC teams hosted FCS opponents and cruised to victory. That said, losses by both USC and Missouri are sure to shake up the rankings.
The Ducks are 10.5-point favorites in the latest Oregon vs. USC odds, while the over/under for total points scored is 59.5, down four points from the opener. Before making any USC vs. Oregon picks, check out the college football predictions from the SportsLine Projection Model .
The No. 15 USC Trojans, led by quarterback Jayden Maiava, face the No. 7 Oregon Ducks, led by quarterback Dante Moore, on Saturday, Nov. 22, 2025 at Autzen Stadium in Eugene, Ore.
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College Football Week 13 Spotlight: EDGE/IDL, Matayo Uiagalelei/A’Mauri Washington vs. USC
CBS Oregon’s late-season date with USC carries playoff implications for both programs, but for NFL watchers Week 13 is also a crucial measuring stick for two front-seven prospects who’ve quietly climbed draft boards.
Fox Sports' Joel Klatt stated on his segment "Contender or Pretender" that he believes USC is a playoff pretender. "Contender," Klatt said. "I think if they beat Oregon, they'll slide all the way up to the 10 spot, so it's very realistic for USC. They are a contender."