Engineered dendritic cells capture tumor EVs, enhancing antigen presentation and T cell activation to boost cancer immunotherapy in preclinical models.

The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response. Their main role is in antigen presentation where ...

Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule known as TAPBPR that optimizes the binding and presentation of foreign antigens across the ...

Philadelphia, February 24, 2023—Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign ...

Recent advancements in cancer vaccine development have demonstrated their potential for precise tumor targeting through antigen-specific immune activation. Nevertheless, critical challenges persist in ...

In a newly published review, Professor Xiao-Jun Huang's team at Peking University People's Hospital explore how haploidentical hematopoietic stem cell transplantation (haplo-HSCT), once limited by ...