Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Epstein-Barr virus (EBV) infected and reprogrammed autoreactive B cells in patients with systemic lupus erythematosus (SLE) to become activated antigen-presenting cells. EBV-infected B cells in ...

Study introduces TRACeR-I, a protein platform with broad HLA compatibility, paving the way for advanced immune response engineering and disease-specific targeting. Study: Targeting peptide antigens ...

Cancer immunotherapy has completely changed our understanding of how cancer can and should be treated. A prime example is chimeric antigen receptor (CAR) T-cell therapy, where T cells are harvested ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...