Chemical synthesis and peptide ligation techniques have revolutionised the field of protein engineering by enabling the precise construction of peptides and proteins with tailored modifications. These ...
Based at the School of Chemistry, our alternative to the traditional PhD offers a unique training period designed to strengthen your research techniques and introduce new technologies and digital ...
This article explores limitations of chemical synthesis in high-throughput settings and the technical advantages enzymatic ...
In a recent review article, a research team outlined recent progress in transition metal-free techniques to achieve coupling. Their combined efforts in these methods could help minimize waste and ...
Scientists have long considered ketones (a fundamental chemical class) and esters (molecules formed when an acid reacts with an alcohol) to be locked treasure chests of possibilities. Ubiquitous as ...
DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...
There’s been this dream for decades. What if we could just print out an entire gene directly, one base at a time? —Daniel Lin-Arlow, Ansa Biotechnologies As scientists set their sights on cell and ...
While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...
A new study has revealed for the first time how different synthesis methods can profoundly impact the structural and functional properties of high entropy oxides, a class of materials with ...
Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...
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Metal-free alternative: Rethinking coupling methods for more sustainable organic synthesis
Coupling reactions are among the most transformative tools in organic chemistry, enabling the formation of crucial chemical bonds in pharmaceuticals, agrochemicals, and advanced materials. Since their ...
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