Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.
Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...
Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial ...
Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...
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DNA twisting controls how cells respond to estrogen
Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...
Understanding the dynamic behavior of DNA remains an important challenge to biophysics, in particular the folding and stretching of DNA is critical since protein-DNA interactions require that the ...
Research chemists have a found a class of synthetic molecules that could quite literally act as a key which could lock away sections of DNA into a closely wound coil preventing proteins from ...
Oestrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the ...
Single-molecule real-time (SMRT) DNA sequencing 1 has opened many avenues in genomic interrogation 1,2,3. In SMRT sequencing, DNA strand replication by an individual DNA polymerase is optically ...
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