Researchers have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -- a new but largely unrealized approach to the treatment of disease.

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins - a new but largely ...

SMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution) Further analysis of PifA and PifB revealed that they exhibit many of the characteristics of eukaryotic host-associated ...

Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the ...

A GIF showing a protein mimicking IL-2 binding to IL-2 receptors, then changing shape in response to an effector molecule, which forces it off of one of the receptors. A protein mimicking IL-2 called ...

The bacterial pathogen Xanthomonas citri, which causes canker disease in citrus trees, activates selected parts of the fruit ...

Proteins are a bit like lights in your house. They have a job to do, and getting them to do it involves switching them on and off with other proteins or molecules. But it’s much easier to flip the ...

We often think of proteins as immutable 3D sculptures. That’s not quite right. Many proteins are transformers that twist and change their shapes depending on biological needs. One configuration may ...

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins — a new but largely ...