We have a GUI for one of the applications I work on that's written almost entirely in Python + PyQt. Everything voxmea said is true, for all good and all ill.

Build your own desktop application using Python and PyQt, one of Python's most popular GUI frameworks. The tutorial covers the basics of PyQt, including installation, creating UI components ...

This module introduces how to develop Graphical User Interfaces (GUI) by ‘dragging and dropping’ various application parts in Python. Specifically, to accomplish this task a program called PyQt will ...

Not every programmer likes creating GUI code. Most hacker types don’t mind a command line interface, but very few ordinary users appreciate them. However, if you write command line programs i… ...