Could Khalil Shakir be poised for one of his biggest games of the year? Is DJ Moore playable again? Check out all of Michael Florio's WR starts and sits for Week 13 of the 2025 NFL fantasy season.

The 2025 Week 13 NFL schedule kicks off on Thursday with the traditional Thanksgiving tripleheader. Check out our full slate fantasy football breakdown of Packers-Lions, Chiefs-Cowboys, and Bengals-Ravens.

The NFL is serving up a three-game Thanksgiving slate of NFL matchups in 2025, where we'll be treated to some high-stakes matchups including playoff contenders ... and also the Cincinnati Bengals. There will be stars in each and every showdown, and it should be a thrilling day of football.

All 32 NFL teams are in action in Week 13, as there are three Thanksgiving Day games to dive into and a Black Friday matchup to keep football on all week long.

Check The Sporting News' Week 13 QB fantasy rankings to set your lineups during another bye week. See Tim Heaney's best matchups, top waiver-wire adds, and sleeper streamers for one-QB, superflex, and 2-QB leagues.

The projected top seeds are the Los Angeles Rams -- the No. 1 team in my Power Rankings — and the New England Patriots. The Rams have looked dominant at times, but they lost at home to Mac Jones and the 49ers earlier this year. The Patriots have ripped off nine straight victories, but do you see that team being unbeatable?

In the first game, the Detroit Lions host the Green Bay Packers. The Lions are small favorites in this big NFC North game, and the point total currently sits at 48.5 on BetMGM. The next two Thanksgiving Day games have even higher totals, and considering the teams, it’s not a big surprise.