Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

The illustration depicts how during differentiation cells normally lose their plasticity and ability to acquire new fates.

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell disorder present in approximately 5% of the general population over the age of 50 years. MGUS is characterized ...

In a translational study led by the University of Leipzig Medical Center and the Fraunhofer IZI, researchers have examined how two innovative CAR T-cell therapies targeting the B-cell maturation ...

In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR ...