There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types ...

Figure 1: Identification of TET1 as a novel partner of NANOG. Figure 3: Synergy between NANOG and TET1/TET2 during reprogramming is dependent upon catalytic activity of TET1/TET2. Figure 4: Mechanism ...

Life begins with a tiny orchestra of stem cells, setting the stage for the body’s grand symphony of development. As the performance unfolds, a dynamic interplay of factors takes center stage, ...

New research shows that certain primate stem cells have pluripotency superior to some types derived from mice. The study maps how pluripotency differs among mice, monkeys, and humans, and illustrates ...

Not all stem cells possess an equal potential to produce specialized cell types. The sum potential of a cell to give different specialized cell types is called ‘potency’. ESCs possess pluripotency.

Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency ...

A new super-resolution system microscopy can assess the pluripotency and differentiation of live stem cells, spearheading a new era in stem-cell research and systems biology. This technology can help ...

Multiplex Gene-Expression Assay for Human Induced Pluripotent Stem Cells Recent methods to reprogram human somatic cells in order to create induced pluripotent stem cells (iPSCs) are intended to ...

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without ...

Despite pluripotent stem cells sharing key transcription factors, their maintenance involves distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can function as master ...

Embryonic stem cells are capable of generating all the cell types that compose the organs and systems of the human body. Now, researchers at Pune’s National Centre for Cell Science (NCCS) have found a ...