First described in 1967, ductal carcinoma of the prostate was originally termed endometrioid carcinoma owing to its histologic resemblance to uterine endometrial carcinoma. It was thought to arise ...

Benign mimics present either as common challenges in daily routine practice or may cause diagnostic dilemmas because some are less commonly seen and one may be less familiar in recognizing them. There ...

Primary mucinous tumors and secondary tumors involving the prostate gland are relatively uncommon, however they have important diagnostic, therapeutic, and prognostic implications. The primary ...

High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor of prostatic adenocarcinoma according to virtually all available evidence. This lesion is characterized by cellular ...

SEATTLE -- In the largest known study of its kind, scientists have confirmed that men with high grade prostatic intraepithelial neoplasia or PIN, characterized by abnormal cells in the lining of ...

Note benign prostatic glands for comparison on the left (a) (×200). Cribriform pattern is not recognized as HGPIN in the 5 th edition. On immunostain, HGPIN is positive for racemase and basal cell ...

Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It ...