When RNA malfunctions, it can result in cancer and developmental disorders. Our cells have molecular “machines” that keep RNA “in check” and eliminate RNAs at the right time. Most come equipped with a ...

microRNAs (miRNA) are recently discovered, short segments of RNA, which play vital roles in health and disease. microRNA over- or under-abundance can switch critical disease genes on or off, ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

Shape Therapeutics, a Seattle preclinical stage biotech company developing RNA editing and gene therapy technologies, has raised $112 million. The company’s RNA editing technologies are spun out of ...

(Reuters Health) - Online gamers have uncovered better models for folding RNA molecules than supercomputers housed in some of the world’s most prestigious research labs, according to a new report. The ...

Roche has agreed to license Shape Therapeutics’ RNA-editing technology in a deal worth up to $3 billion. Shape uses adeno-associated viruses to deliver RNA-editing machinery to treat neurological and ...

Obelisks are 1 kb RNA replicators with protein-coding genes and ribozymes Found in 50% of oral and 7% of gut microbiomes, indicating widespread presence Their impact on human health remains unknown ...

Shape Therapeutics has raised $112 million in series B financing to further develop RNA editing and gene-therapy technologies. Shape’s RNA editing technology takes advantage of an enzyme called ADAR ...

Noncoding RNA folds into intricate shapes that determine its function, but the rules of nucleotide patterns that determine these shapes are largely unknown. Now, an online game that tasks users to ...

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present on the leaf ...