Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments. New research published in iScience by ...

Figure 3: Various scaffolds utilized to engineer binders to Ras and their binding epitopes. Ras proteins are small GTPases that regulate cell growth and division. Mutations in Ras genes are associated ...

Assessing the Reliability of Patient, Nurse, and Family Caregiver Symptom Ratings in Hospitalized Advanced Cancer Patients ABSTRACT: Ras proteins are guanine nucleotide–binding proteins that play ...

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key ...

Two original papers in Nature highlight the discovery and translational implications of RMC-7977, a RAS(ON) multi-selective tri-complex inhibitor that exhibits unprecedented anti-tumor activity in ...

A blue protein ribbon structure labeled PI3Kα has a space-filling molecule bound to it, which interacts (clashes) with a second protein ribbon molecule labeled KRas. This model shows how BBO-10203 ...

New findings help better understand the how one of the most commonly mutated genetic drivers of cancer passes signals that cause the disease. New findings by UT Southwestern researchers help better ...

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of ...

A new blood cancer treatment has been found to prevent cancerous cells from growing and multiplying. The treatment works by combining a drug that prevents cancer cells from growing uncontrollably with ...

Relapses in a common form of leukemia may be preventable following new research that has identified how the cancer develops resistance to first line treatments. Relapses in a common form of leukemia ...