Autistic adults show reduced availability of a key glutamate receptor, mGlu5, across widespread brain regions.

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

January 18, 2010 — Individuals with treatment-resistant depression tend to have the G/G genotype associated with higher levels of 5-HT 1A autoreceptors, and turning off some of those autoreceptors ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...

Opioids slot into opioid receptors and activate them. This sends signals to your brain to relieve pain and promote pleasure. Both endogenous opioids, which your body naturally produces, and exogenous ...

Yale School of Medicine (YSM) scientists have discovered a molecular difference in the brains of autistic people compared to ...

"G-protein coupled receptors, normally, can be activated by specific small molecules that bind in a pocket in the receptor," explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists is to control that process, making cells respond how they want to what ...