If you’re in the market for a human skeleton model, it’s probably because you’re a teacher, professor, or student. These three-dimensional models are essential tools to help teach or learn all 206 ...
Scientists are using in vitro skeletal muscle engineering to gain a better understanding of the complex genetic and environmental factors underlying diabetes, putting lab-grown, healthy skeletal ...
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
BOULDER, Colo.--(BUSINESS WIRE)--Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, targeted, small molecule therapies ...
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Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
This genetic model suggests otherwise, indicating that coupled gating or other mechanical interactions, rather than CICR, drive activation of uncoupled RyR1 channels. Interestingly, the researchers ...
A model combing an immune-related genes signature and an extracellular matrix-related genes signature in predicting prognosis of left- and right-sided colon cancer. Genetic variants involved in the ...
Researchers from the Australian Regenerative Medicine Institute (AMRI) at Monash University find that, towards the end of life, muscles “rejuvenate” to resemble their early-life metabolic state in an ...
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