Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

Genes and alleles are essential to basic genetics, but what are the differences between them? In this guide, we compare genes and alleles and provide simple definitions and examples for both. Genes ...

The presence of the single nucleotide variation HLA-DRB1*01:03 was associated with severe ulcerative colitis, according to a Danish genome-wide association study. The association between the ...

Allele frequency is a measure of the relative frequency of an allele on a genetic locus in a population. Usually it is expressed as a proportion or a percentage. In population genetics, allele ...

For 30 years, APOE4 has ranked as the strongest genetic risk factor for Alzheimer’s disease, with two copies boosting the odds up to 15-fold. Now, scientists argue that people with two APOE4 alleles ...

Your genes are made of DNA. This DNA provides instructions, which determines traits like your hair color and blood type. There are different versions of genes. Each ...