Christian McCaffrey forced 11 missed tackles, closing in on a new career high as his running keeps the 49ers’ offense on track.

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago.

"We do it all the time in practice, so it's not a big deal," Trent Williams said of McCaffrey's untouched TD. "But yeah, it's pretty cool."

Christian McCaffrey galloped for 142 yards and the San Francisco 49ers defense allowed just 230 to power a primetime win over the Carolina Panthers.

The San Francisco 49ers have transformed their offense since acquiring Christian McCaffrey from the Carolina Panthers three years ago.

The 49ers packaged a second-, third- and fourth-round pick in 2023 and a fifth-rounder in 2024 for McCaffrey from the Panthers.

The 49ers and Panthers are in the thick of the NFC playoff race. Follow along for the latest updates as they face off on "Monday Night Football."

After receiving the opening kickoff, the 49ers went on a 15-play, 72-yard drive that ended with a 12-yard touchdown pass from Brock Purdy to Jauan Jennings. Purdy completed six of seven passes for 33 yards on the drive,