Sinner was playing against Carlos Alcaraz in the Cincinnati Open final on Monday night, but retired with an unspecified illness at 5-0 down in the first set, and has now pulled out of the US Open tournament.

Follow scores and live text updates from the US Open mixed doubles as Jack Draper and Jessica Pegula take on Mirra Andreeva and Daniil Medvedev in the quarter-finals.

The US Open senior director of player relations Eric Butorac joined John Isner, Jack Sock and Sam Querry on the Nothing Major podcast ahead of the mixed doubles tournament. And he revealed that Sinner had expressed an interest to play with Williams, who won six US Open singles titles during her career.

Sinner received heartfelt commiserations from his opponent and chief rival Carlos Alcaraz, who won each of five games that were completed. Alcaraz thus collected his third straight Masters 1000 title of a fine season that has also seen him defeat Sinner in the French Open final before losing to him at Wimbledon.

Grand Slam singles champions such as Jannik Sinner, Carlos Alcaraz, Iga Swiatek and Madison Keys will be playing for extra money — $1 million to the winning duo — and trying to get their hands on a trophy in the U.

The women's British No1's pairing with the five-time Grand Slam champion was arguably one of the most heavily anticipated of the new-look doubles event at Flushing Meadows.