A deep spatial proteomic analysis of healthy fallopian tube epithelium, matching high-grade serous ovarian cancer (HGSOC) ...
The endoplasmic reticulum (ER) and mitochondria form contacts that support communication between these two organelles, including synthesis and transfer of lipids, and the exchange of calcium, which ...
The photoreceptors required for post‐translational regulation of CO have been characterized. Mutations in the genes encoding the photoreceptors phytochrome A (phyA) and cryptochrome 2 (cry2) delay ...
Sodium (Na +) is an alkali cation, which is not accumulated at large concentrations in most plant cells, in contrast to the alkali cation potassium (K +), which is an essential macronutrient for plant ...
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While such loss‐of‐function mutagenesis is a powerful approach to the genetic dissection of signal pathways (Glazebrook, 2001), many genes cannot be uncovered in this way because of lethal effects or ...
Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...
Mutations in fused in sarcoma (FUS) are a cause of familial amyotrophic lateral sclerosis (fALS). Patients carrying point mutations in the C‐terminus of FUS show neuronal cytoplasmic FUS‐positive ...
Posttranslational modifications expand the diversity of the proteome enormously, with protein glycosylation being the most abundant and diverse form of modification serving different functions for ...
Processes vital to life such as respiration and photosynthesis critically depend on the availability of tetrapyrroles including hemes and chlorophylls. tRNA‐dependent catalysis generally is associated ...
TIA1 is a prominent RNA binding protein (RBP) involved in the formation of pathogenic aggregates in neurons. This manuscript shows that the annexin protein family member ANXA7 links TIA1 granules to ...