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Georgia Tech dropped in the rankings after a loss which opens a clear path back to the ACC Championship for the Mustangs.
The Louisville Cardinals were in a great spot to secure a berth in the ACC Championship, but their dreams have been dashed by back-to-back losses to California
Expert recap and game analysis of the SMU Mustangs vs. Louisville Cardinals NCAAF game from November 22, 2025 on ESPN.
Louisville Cardinals vs SMU Mustangs Prediction, 11/22/2025 College Football Picks, Best Bets & Odds
The SMU Mustangs (7-3) will try to defeat the Louisville Cardinals (7-3) at Gerald J. Ford Stadium on Saturday, November 22, 2025. SMU opens this matchup as 3.0-point favorites from Vegas oddsmakers. The total is set at 52.5.
Of course, the rankings that truly matter don't come out until Tuesday when the College Football Playoff committee unveils its latest ordering of the teams. But
SMU football has shown no rookie fatigue in its first season in the Atlantic Coast Conference. At 11-1 overall on the season, the No. 7 Mustangs played for their first ACC title on Saturday against one of the conference's powerhouse programs, No. 17 ...
The Louisville Cardinals play against the SMU Mustangs in an ACC football game today. Fans can watch this game for free online.
At the end of the season, SMU will say goodbye to a senior class that helped lead the Mustangs back to national prominence.
The SMU Mustangs (7-3) play a conference opponent when they host the Louisville Cardinals (7-3) on Saturday, November 22, 2025 at Gerald J. Ford Stadium in an ACC battle. The Mustangs enter the matchup after winning 45-13 over the Boston College Eagles in their last outing on Nov. 8. The Cardinals' last game was a 20-19 loss to the Clemson Tigers.
An undermanned Louisville team went into Dallas and left with a loss to the SMU Mustangs. After getting the opening kick, SMU took little time to get their offense going. The Mustangs were helped out by two pass interference calls on Jabari Mack, but they capitalized on the opportunities. A boot leg for Kevin Jennings gave SMU a 7-0 lead.
The Louisville Cardinals have an intriguing situation at quarterback if Miller Moss is unable to take part in their matchup against SMU.
The Los Angeles Rams look like the best team in football after their sixth straight win on Sunday. There was never a doubt as they took down the Buccaneers 34-7
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