The coronavirus disease 2019 (COVID-19) pandemic underscored the need for the development of tools that can visualize immune system activity in the context of viral inflammation. Although [18F]FDG PET ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

See an invited perspective on this article on page 1412. Tumor growth and spread are determined not only by cancer cells but also by the nonmalignant constituents of the malignant lesion, which are ...

Good-manufacturing-practice–grade precursor DOTA-Siglec-9 was obtained from ABX Advanced Biomedical Compounds GmbH. All other reagents were purchased from commercial suppliers and were either ...

Pharmacokinetics of radiopharmaceuticals (e.g., radioimmunotherapy agents) are assumed to follow first-order kinetics and are, therefore, approximated by the sum of discrete rates (1–3). However, the ...

See an invited perspective on this article on page 466. We believe that the PSMA-RADS system is most useful for the categorization of lesions outside the prostate. The reason for that is twofold.

TO THE EDITOR: Peptide receptor radionuclide therapy (PRRT) is highly effective in neuroendocrine tumors (NETs). In the NETTER-1 trial, progression-free survival at month 20 in patients with advanced ...

Diagnostic Accuracy of Fully Hybrid PET/MRI with [68 Ga]Ga-PSMA-11 and [68 Ga]Ga-RM2 in Detecting Primary Prostate Cancer: A Phase 2 Trial with Histology as Gold Standard ...

Today's medical imaging technologies are expected to furnish anatomic, physiologic, molecular, and genomic information for accurate disease diagnosis, prediction of treatment response, and development ...

The purpose of this Procedure Guideline is to assist physicians in recommending, performing, interpreting, and reporting the results of SPECT/CT for imaging of adult and pediatric patients. SPECT is a ...

SPECT is a rapidly changing field, and the past several years have produced new developments in both hardware technology and image-processing algorithms. At the component level there have been ...

Somatostatin receptor (sstr) scintigraphy for imaging and sstr analogs for treatment have been used for more than 20 y. An important improvement in recent years was the introduction of peptide ...