Tumors trigger T-cell exhaustion through a TSP-1–CD47 signaling pathway. Blocking it can restore immune strength and improve cancer treatment.

The Fugaku supercomputer builds a highly detailed virtual mouse cortex with millions of neurons enabling unprecedented ...

AAV-SLB101 is a rationally designed capsid developed for enhanced skeletal muscle, cardiac tropism, and reduced biodistribution to the liver.

Prophylactic HPV vaccines prevent infection but not existing disease. A nasal nanogel vaccine shows preclinical promise for ...

Microrobots could be precisely directed, under clinical conditions, by integrating systems for navigation, therapeutic ...

Korro Bio saw its stock reach all-time lows on disappointing data for its lead pipeline candidate, while Intellia Therapeutics saw analyst downgrades on safety concerns despite releasing positive data ...

Merck & Co. has agreed to acquire Cidara Therapeutics for approximately $9.2 billion, the companies said, in a deal designed to bolster the buyer’s antiviral portfolio with a Phase III drug designed ...

Animal testing is costly, slow, and poorly predictive. ORIVA offers a human-relevant alternative with the potential to change that.

Engineered human stomach organoids, transplanted into mice, produced insulin-secreting cells, offering a potential new ...

GATC brought together a broad coalition of researchers and executives in cell and gene therapy, gene editing, drug discovery and AI as well as patients and advocates.

Findings suggest that urinary ceramide levels could serve as an early biomarker for acute kidney injury, helping doctors identify patients at risk.

Multiomics analysis of immune rejection of a pig kidney transplanted into a human decedent uncovers key antibody and T cell responses.