PURPOSE:The aim of this study was to examine if sparging with CO2(g) could be used to establish stable biorelevant bicarbonate buffers, in aqueous medium, for use in dissolution characterization of ...

University of Michigan, College of Pharmacy, Department of Pharmaceutical Sciences, 428 Church Street, Room 4002, Ann Arbor, Michigan 48109, United States ...

The bicarbonate buffer is considered as the most biorelevant buffer system for the simulation of intestinal conditions. However, its use in dissolution testing of solid oral dosage forms is very ...

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan Department of Biochemistry, Juntendo University Graduate School of Medicine, Tokyo ...

Researchers have identified this receptor in brain mural cells that regulates reperfusion injury. Optimal pH homeostasis for cellular function is maintained by the acid-base balance through multiple ...

Internal acid–base homeostasis is fundamental for maintaining life. Accurate and timely interpretation of an acid–base disorder can be lifesaving, but the establishment of a correct diagnosis may be ...

N-2-Hydroxyethylpiperazine-N'-2-ethane sulfonic acid (HEPES) and N-tris(hydroxymethyl)methyl-2-aminoethane sulfonic acid (TES) have been found to be non-toxic substitutes for bicarbonate buffer in ...

Please provide your email address to receive an email when new articles are posted on . BOSTON — Adding sodium bicarbonate to steroid lidocaine injections for patients with certain hand conditions who ...