Reviving an ancient human gene that prevents gout and fatty liver disease, scientists at Georgia State University have marked ...

The real revolution came in 2012, when researchers Jennifer Doudna and Emmanuelle Charpentier harnessed CRISPR, a natural bacterial defense system. In bacteria, CRISPR cuts out invading viruses’ DNA ...

By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human ...

Gout is one of the oldest documented human illnesses. It develops when sharp crystals form inside joints, triggering intense swelling and pain, and is ...

A study of mosquitoes’ circadian rhythms finds they hunt differently at different times of day. It could help stop their ...

The FDA’s Marty Makary and Vinay Prasad have laid out a path for CRISPR treatments on demand. An expert weighs in on what it ...

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, ...

CRISPR-based technology is advancing rapidly, driving international competition. Its promise to transform medicine is colliding with political and social realities, even as applications expand.

Promising results from a small clinical trial highlight a growing interest in designing gene-editing treatments for common ...

One person’s side effect could be another person’s treatment if we expand our perspective on small molecule drug targets, ...

Marty Makary and Vinay Prasad offered a roadmap for expanding access to custom gene-editing treatments like the one used to treat Baby KJ's ultra-rare disease.

Penn and CHOP researchers want to develop urea cycle disorder treatments using CRISPR gene-editing therapy. Get unlimited access to Inquirer.com and The Inquirer App, plus 5 articles each month to ...