If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Imagine if our bodies could grow new organs throughout our entire lives. Plants do this constantly, thanks to tiny, powerful ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, ...