One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce ...