Colorado Buffaloes fans will be watching closely this Sunday when rookie quarterback Shedeur Sanders makes his first home ...

Head coach Kyle Shanahan and defensive coordinator Robert Saleh detailed the team's injury updates, praised the growth of their young defenders, and outlined the challenges of facing the Cleveland ...

Brandon Aiyuk reportedly missing offseason rehab appointments played a role in the San Francisco 49ers voiding guarantees in his contract.

Also: Tom Brady's Raiders frustrations, Kyle Shanahan's latest masterpiece and the NFL storylines that will carry ...

Panthers despite Brock Purdy's rough night. A look at what went right, what went wrong, and why San Francisco's playoff hopes ...

The San Francisco 49ers trusted Christian McCaffrey to get the job done against his former team. As it usually happens, that turned out to be the ...

The San Francisco 49ers will take wins where they can get them after injury woes threatened to derail their season. But Brock ...

San Francisco receiver Jauan Jennings responded to a cheap shot from Carolina safety Tre’Von Moehrig late in Monday night’s ...

The 49ers and Panthers are in the thick of the NFC playoff race. USA TODAY Sports provided updates, highlights and more from ...

In the modern NFL, safety play is destiny. If Brown has leveled up alongside the equally violent Malik Mustapha, the Niners ...

Week 12 of the regular season closes with an intriguing matchup between a surprising team seeking a statement road win against a franchise trying to prove it still belongs among the NFL's top tier of ...

McCaffrey, one of the best receiving running backs in NFL history, plays his former team on "Monday Night Football." ...