Scientists are using in vitro skeletal muscle engineering to gain a better understanding of the complex genetic and environmental factors underlying diabetes, putting lab-grown, healthy skeletal ...
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
BOULDER, Colo.--(BUSINESS WIRE)--Edgewise Therapeutics, Inc., (Nasdaq: EWTX), a clinical-stage biopharmaceutical company focused on developing orally bioavailable, targeted, small molecule therapies ...
Dyno Therapeutics, Inc., a genetic technologies company applying artificial intelligence (AI) to solve the grand challenge of in vivo gene delivery, announced Dyno-bn8, a novel adeno-associated virus ...
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Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
This genetic model suggests otherwise, indicating that coupled gating or other mechanical interactions, rather than CICR, drive activation of uncoupled RyR1 channels. Interestingly, the researchers ...
Researchers from the Australian Regenerative Medicine Institute (AMRI) at Monash University find that, towards the end of life, muscles “rejuvenate” to resemble their early-life metabolic state in an ...
Muscles can only contract and relax, so they always work in pairs called antagonistic muscles. Skeletal muscle is joined to bones. Its cells contract to make bones move and joints bend. Skeletal ...
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