Scientists determined the cryo-EM structure of IGF Ternary complex and its assembly and activation mechanism. Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses ...

Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, ...

Protein-protein interactions are essential for maintaining cell structure and for executing almost all cellular processes. Determination of where and how each protein interacts with its partners ...

Chromatin is the complex of DNA and proteins that makes up the genetic material in the nucleus of eukaryotic cells. A chromatin modifier is a protein or complex of proteins that chemically modifies ...