We get a QB-WR stack of sorts from the Rams and an underrated runner as the favored bets of Week 12's penultimate game.

That continued a three-week NFL betting trend that has seen ’dogs pay off at a 58.1% rate against the number (25-18 ATS). And while sizable favorites — those laying 4 points or more — are a robust 57-18-1 this season straight up, they’re just 36-40 ATS.

Texans (+5.5) over Bills. Buffalo's defense is reeling at the moment, allowing 30 or more points in back-to-back games. The Bills' run defense has been abysmal, surrendering 5.4 yards per carry (second most in the NFL). That could result in a strong day for the Texans on the ground, which could help tip the scales in favor of an upset.

Myles Garrett has seven games to record eight sacks and take down Michael Strahan's record of 22.5 in a single season. Can he do it? See the odds and more.

The Colts look to avoid back-to-back losses for the first time when they go to Olympiastadion in Berlin, Germany. Indianapolis dropped its second game of the season against Pittsburgh, 27-20, while Atlanta lost a nail biter to New England, 24-23.

In a Week 11 NFL slate that includes plenty of exciting contests, the Seattle Seahawks versus the Los Angeles Rams is a game to catch. If you're seeking additional betting information for Week 11 in the NFL, we have you covered with betting odds for all the important matchups.

NFL Week 11 betting spreads, lines, point totals for every game on NFL Week 11 schedule, with odds for favorites and underdogs in each NFL matchup.

Jacoby Brissett is a fine backup and can give you a chance in small doses, but the more he plays, the more you realize why he is a career backup. They have injury issues at wide receiver with Zay Jones sidelined and Marvin Harrison Jr. still questionable. The defense has allowed 85 points over the past two games.

Here are Jets Wire's three key matchups to watch during the Jets' matchup with the Ravens: CB Jarvis Brownlee vs. WR DeAndre Hopkins. Hopkins moves inside and out of the Ravens of