The Los Angeles defense has been excellent this season, but Baker Mayfield is going to show up for a primetime game, especially if he ends up getting Bucky Irving and Chris Godwin back. Even if he doesn't, the Bucs should be able to get to 20+ points in this spot.

NFL Week 11 kicked off Thursday night, as the Patriots beat the Jets. Here are the lines for every Week 11 matchup at DraftKings Sportsbook as of Nov. 15. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

That continued a three-week NFL betting trend that has seen ’dogs pay off at a 58.1% rate against the number (25-18 ATS). And while sizable favorites — those laying 4 points or more — are a robust 57-18-1 this season straight up, they’re just 36-40 ATS.

Our NFL Week 12 early picks against the spread start with Josh Allen and the Bills vs. the Texans on Thursday night.

Josh Inglis' NFL TD picks and best bets on NFL TD props for every NFL Week 12 game — plus our best NFL TD parlay!

NFL Week 11 betting spreads, lines, point totals for every game on NFL Week 11 schedule, with odds for favorites and underdogs in each NFL matchup.

Jacoby Brissett is a fine backup and can give you a chance in small doses, but the more he plays, the more you realize why he is a career backup. They have injury issues at wide receiver with Zay Jones sidelined and Marvin Harrison Jr. still questionable. The defense has allowed 85 points over the past two games.