GLENDALE -- The Arizona Cardinals' latest loss just might be their most head-scratching. The Cardinals' 27-24 overtime defeat to the Jacksonville Jaguars came down to the final play - though when all was said and done, Arizona dropped their eighth game within the last nine weeks.

Arizona Cardinals quarterback Jacoby Brissett is dealing with an injury in the second half of the Week 12 game against the Jacksonville Jaguars.

The NFL season continues in Week 12 when the Arizona Cardinals host the Jacksonville Jaguars on Sunday. Start time, how to watch, stream and NFL TV schedule.

STATE FARM STADIUM -- The Arizona Cardinals fell to the Jacksonville Jaguars in 27-24 overtime fashion in Week 12, marking their eighth loss in nine games. The Cardinals can't stop sliding down the standings after their 2-0 start, though their latest loss might be the most controversial thanks to Arizona's final play-call to end the game.

Highlights from the Week 12 performance of Jacksonville Jaguars quarterback Trevor Lawrence during the 2025 NFL season against the Arizona Cardinals where he threw 3 touchdown passes.

After a historic five-game stretch of one-score losses, the Cardinals are once again on the wrong side of history with their loss to the Jaguars.

GLENDALE -- In Walter Nolen's fourth NFL game, he managed to score quite the impressive touchdown to level things at 7-7 between the Arizona Cardinals and Jacksonville Jaguars. In the first quarter, Jaguars QB Trevor Lawrence was hit while dropping back to pass by Cardinals safety Jalen Thompson - popping the ball loose.