NFL Week 13 picks, predictions, win probabilities for Packers-Lions, Rams-Panthers, Texans-Colts, Vikings-Seahawks, Raiders-Chargers, games this week.

The New England Patriots are in the driver's seat for the No. 1 seed in the AFC, and they have one more game to win before they head into their Week 14 BYE. Thi

There are approximately 74 people left in our large pool of 931, and I have used the following teams: Arizona, Dallas, Tampa Bay, Houston, Detroit, L.A. Rams, Kansas City, Indianapolis, L.A. Chargers, Denver, New England and Seattle.

Undrafted rookie Max Brosmer will start for Minnesota due to J.J. McCarthy entering the concussion protocol, and at 11.5 points for the biggest spread of the week, Mike Florio and Chris Simms like Seattle to cover.

The projected top seeds are the Los Angeles Rams -- the No. 1 team in my Power Rankings — and the New England Patriots. The Rams have looked dominant at times, but they lost at home to Mac Jones and the 49ers earlier this year. The Patriots have ripped off nine straight victories, but do you see that team being unbeatable?

Colin Cowherd lists his best bets entering Week 13 of the 2025/26 NFL season, including the Detroit Lions, Miami Dolphins, and Tampa Bay Buccaneers.