Border Patrol agents near San Diego seized 22 pounds of fentanyl, cocaine and heroin hidden in child booster seats, officials ...

OCEANSIDE, Calif — A 25-year-old Oceanside man was arrested Monday in connection with the death of his 83-year-old neighbor.

A fiery collision in Scripps Ranch left five people hospitalized, with one in critical condition. The crash closed roads, ...

Travelers this Thanksgiving may still feel on edge after the historic government shutdown that caused widespread flight ...

Anders Dreyer scored in the second half and Pablo Sisniega made three saves to lead expansion side San Diego FC to a 1-0 ...

WASHINGTON — Medical Products Laboratories Inc. is voluntarily recalling more than 41,000 bottles of Walgreens-branded saline nasal spray after discovering bacterial contamination in the product.

In response to construction projects, Cal State San Marcos has found ways to preserve the greenery and landscape on campus ...

Nobody has won the jackpot since Sept. 6, when two tickets matched all six numbers to claim a staggering $1.8 billion prize.

The up-and-coming artist, who performed under the stage name DELAROSA, had released her first song in August, "No Me Llames." ...

Mel Vernon, a champion of Luiseño heritage, is November's Constituent of the Month. Discover how he's keeping history alive in North County San Diego!

ENCINITAS, Calif. — A driver was arraigned today on vehicular manslaughter charges in connection with the death of ...

Orfila Winery faces backlash over a giraffe's presence at their event, leading to member cancellations and a PETA complaint.