Improvements in medical therapy, carotid-artery stenting, and carotid endarterectomy call into question the preferred ...

This feature about a man hospitalized for uncomplicated diverticulitis who is found to have high blood pressure offers a case vignette accompanied by two essays, one supporting watchful waiting and ...

A 26-year-old woman was referred to the pulmonary hypertension clinic with a 6-month history of exertional dyspnea and hoarseness. Vocal-fold paralysis was seen on laryngoscopy (shown in a video).

Joshua Barocas is an associate professor of medicine at the University of Colorado Anschutz Medical Campus. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal.

A 79-year-old man was admitted to a hospital in Guangzhou, China, with progressive dyspnea and edema. Echocardiography and ...

Personalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The FDA outlines a path to market entry for products where a randomized trial is no ...

To the Editor: The results of the C-POST trial, reported by Rischin and colleagues (August 21/28 issue), 1 highlight improvements in disease-free survival with adjuvant cemiplimab. As the authors ...

We conducted an international, open-label, randomized, blinded-outcome-assessment trial involving 1284 patients who had undergone successful catheter ablation for atrial fibrillation at least 1 year ...

A federal appeals court ruling in United States v. Safehouse may open the door to a new legal defense for harm-reduction interventions in a hostile political climate.

The cytokine A proliferation-inducing ligand (APRIL) is considered a key driver of the pathogenesis of IgA nephropathy. Sibeprenlimab, a humanized IgG2 monoclonal antibody, selectively binds to and ...

Approximately 5 million persons in the United States have psoriasis. 1 Most have mild disease covering less than 3% of body-surface area, but approximately one fifth have more extensive involvement ...