Berkshire Hathaway, Buffett’s investment group, disclosed it had bought 5 million shares of the healthcare company earlier in the year. That sparked a 14% Friday rally in a stock that has lost more than half of its value over the past 12 months.

So while we should always try to assess where a stock or sector is headed, the better way to trade is with a simple framework: Any stock can go up and thus be a source of profits. However, owning each stock comes with different levels of risk,