The illustration depicts how during differentiation cells normally lose their plasticity and ability to acquire new fates.

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Background Withdrawal of prolonged nucleos(t)ide analogue (NA) treatment results in hepatitis B surface antigen (HBsAg) loss in some subjects with chronic hepatitis B (CHB), potentially revealing ...

Epstein-Barr virus (EBV) infected and reprogrammed autoreactive B cells in patients with systemic lupus erythematosus (SLE) to become activated antigen-presenting cells. EBV-infected B cells in ...

About five million people worldwide have systemic lupus erythematosus (SLE), an autoimmune disease that damages organs and tissues throughout the body, including skin, joints, kidneys, heart, and ...

This work reveals metabolic pathways and molecular events mechanistically linked to B cell activation. Using an unbiased, comprehensive proteome profiling method and various functional validation ...

Three draft recommendation documents published on Wednesday are intended to guide drug sponsors and accelerate the development of cell and gene therapies. The FDA has published three draft ...

Funding fuels expansion of the country’s most established developmental therapy model. Series C round led by aMoon Fund, B Capital and Flare Capital Partners with participation from Healthworx, ...

Welcome to my journey of success, as an Orthopedic Surgery Resident at the Mayo Clinic! 🏥💪 Here, we dive into evidence-based strategies for human performance, academic excellence, and professional ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. In this case series, four ...