Researchers at Karolinska Institutet and KTH have developed a computational method that can reveal how cells change and ...
AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
We used single-cell and high-resolution spatial transcriptomics to investigate age-related decline in mouse skeletal muscle regeneration. Using a transfer learning-based scoring approach, we ...
Genetic circuit engineering is the synthesis of unnatural DNA segments encoding protein or RNA molecules that control each other’s levels. Genetic circuit engineering is the bottom-up, local approach ...