Brock Purdy throws career high 5 TD passes and leads 49ers to 5th straight win, 48-27 over the Colts

Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead the San Francisco 49ers to a 48-27 victory at Indianapolis.

Brock Purdy's career-high five TD passes power 49ers past Philip Rivers' Colts on 'Monday Night Football'

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...