Electron microscopy revealed approximately 40–50 nm particles with crenated edges; immunogold labeling placed AGO2 and sialylated glycans at their perimeters, consistent with prior reports that ...
This study provides valuable data on the role of Hsd17b7, a gene involved in cholesterol biosynthesis, as a potential regulator of mechanosensory hair cell function. The authors used both zebrafish ...
This important study presents a technically rigorous and carefully controlled analysis of the signalling potential of cancer-associated gain-of-function Notch alleles. The work is clearly presented, ...