Brock Purdy's three interceptions did little to stand in the way of another San Francisco 49ers victory as they took care of ...

Christian McCaffrey forced 11 missed tackles, closing in on a new career high as his running keeps the 49ers’ offense on ...

McCaffrey made history again in Monday’s game, prompting a big announcement from the NFL.

Christian McCaffrey galloped for 142 yards and the San Francisco 49ers defense allowed just 230 to power a primetime win over ...

In only his third NFL season, running back Christian McCaffrey became the third player in NFL history to run for 1,000 yards ...

"We do it all the time in practice, so it's not a big deal," Trent Williams said of McCaffrey's untouched TD. "But yeah, it's ...

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three ...

McCaffrey gains 142 yards from scrimmage (89 rushing) and scores a touchdown in a 20-9 win, his first game against his former ...

San Francisco 49ers running back Christian McCaffrey had a memorable performance against his former team, Carolina Panthers, ...

The loss left the Panthers a half-game behind Tampa Bay (6-5) in the division with their next game against the NFC-leading ...

San Francisco 49ers running back Christian McCaffrey takes the toss and bursts into the end zone for a 12-yard touchdown run ...