San Francisco 49ers kicker Matt Gay connects on a 47-yard field goal to extend the 49ers lead to 10-3 over the Carolina ...

San Francisco 49ers quarterback Brock Purdy connects with tight end George Kittle over the middle for a 25-yard gain into ...

Peyton Manning and Eli Manning show a viral video of Carolina Panthers 'theme song' with country singer and Panthers fan Luke ...

Peyton Manning and Eli Manning break down Carolina Panthers cornerback Jaycee Horn's second interception against the San Francisco 49ers.

Carolina Panthers kicker Ryan Fitzgerald connects on a 25-yard field goal to trim the San Francisco 49ers lead to 7-3.

Carolina Panthers running back Rico Dowdle makes multiple San Francisco 49ers defenders miss on an incredible spin move that ...

Carolina Panthers cornerback Jaycee Horn jumps the route and intercepts San Francisco 49ers quarterback Brock Purdy for the second time tonight.

San Francisco 49ers running Christian McCaffrey puts the ball on the ground but offensive tackle Colton McKivitz is somehow ...

Carolina Panthers cornerback Mike Jackson leaps up and snatches an incredible interception in the end zone off San Francisco ...

San Francisco 49ers quarterback Brock Purdy eludes multiple Carolina Panthers defenders and runs for a 9-yard first down.

On the ManningCast of Monday Night Football with Peyton and Eli, Hall of Fame quarterback Peyton Manning and former NFL ...

San Francisco 49ers running back Christian McCaffrey makes a Carolina Panthers defender miss on a wicked juke move on a ...