The Panthers were considered big underdogs for tonight's game against Santa Clara, and the oddsmakers were right to think so.

If the 49ers make the playoffs McCaffrey might start to feel the effects of the 400-plus touches he’s on pace for, but that’s ...

NFL Week 13 odds, picks, predictions, TV channel, streaming information for the Sunday football game between San Francisco ...

The San Francisco 49ers beat the Carolina Panthers 20-9 despite Brock Purdy’s 3 INTs. Colin Cowherd discusses the QB’s return ...

The San Francisco 49ers did not play their best game against the Carolina Panthers on Monday Night Football last night.

Jauan Jennings and Tre’Von Moehrig were involved in a confrontation after Monday night’s game between San Francisco 49ers and ...

The Niners defense limited the damage from three first-half interceptions by Purdy and the offense turned conservative in the ...

Browns coach Kevin Stefanski said rookie Shedeur Sanders will remain the starting quarterback when Cleveland plays host to the San Francisco 49ers.

San Francisco 49ers quarterback Brock Purdy will have to find ways to be effective despite the cold weather on Sunday.

The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

Three first-half interceptions turned Purdy into a dink-and-dunker for the rest of the game. The 49ers need the good Purdy ...

George Kittle explained how the San Francisco 49ers maintain their standard despite injuries after the Week 12 win vs. the ...